Pathology and Stem Cell research center

Introduction:

Pathology and stem cell research center affiliated with Afzalipour School of Medicine has been established with great efforts done by Presidential Administration of Iran, Research Deputy of Ministry of Health and Medical Education, Dr. Vasei, and a group of faculty members at Kerman University of Medical Sciences in 2011. This center consists of different sections such as cell culture, Molecular Pathology, Western Blot, Flow Cytometry, and Histopathology and has the diagnostic medical services capabilities such as BCR-ABL, JAK2, HLA Typing, Karyotyping, Fish, Cish, and BK. It has to be said that this center has had effective activity in conducting research projects and theses on Cellular and Molecular Pathology, the output of which is publishing 45 articles in well-known international journals in the recent three years and collaboration in 200 research projects with other organizations and research centers such as Physiology and Neuroscience, Departments such as Haematology, Biochemistry, Parasitology, Medical Mycology, Immunology from medical university and departments of Chemistry, Biology, Agriculture, and Veterinary from Shahid Bahonar University of Kerman and School of Pharmacy and Pharmaceutical Sciences and Leishmaniasis Research Center. During recent years the center has employed many PhD-by-research medical students and the staff from compulsory medical service program. Holding two Afzalipour international medical congresses on pathology in 2015 and 2018 in Kerman is among the credits of the center. This center has expert staffs who have held 30 different workshops on Cellular and Molecular techniques. The center as a subset of Kerman University of Medical Sciences intends to take measures in scientific enhancement of Iran.

Research activities:

1. Peripheral blood derived mesenchymal stem cells: growth factors-free isolation, molecular characterization and differentiation
2. A New Indole Derivative Decreased SALL4 Gene Expression in Acute Promyelocytic Leukemia Cell Line (NB4)
3. Molecular Pathology and Histopathological Findings in Localized Leishmanial Lymphadenitis
4. Isolation and Evaluation of Dental Pulp Stem Cells from Teeth with Advanced Periodontal Disease
5. Molecular Identification of Common Leishmanial Parasites by the Gene ITS2-rRNA by different method Targeting to Provide Real-time PCR Technique to Determine the Parasite Load
6. Design and Validation of Real-Time PCR: Quantitative Diagnosis of Common Leishmania Species in Iran
7. Maspin Gene Expression in Invasive Ductal Carcinoma of Breast
8. Fast Method for Diagnosis of Leishmania by PCR and FLASH PCR
9. Methylenetetrahydrofolate Reductase Polymorphisms in Iranian Patients with Glanzmann’s Thrombasthenia
10. Comparison of the Frequency of Y-short Tandem Repeats Markers between Sadat and Non-Sadat Populations in Isfahan Province of Iran
11. Assessment of nuclear and mitochondrial genes in precise identification and analysis of genetic polymorphisms for the evaluation of Leishmania parasites
12. Fibrin scaffold enhances function of insulin producing cells differentiated from human umbilical cord matrix-derived stem cells